Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | POLRMT | O00411 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355478 | 0.93 | POLRMT (0.41) | TMPRSS2POLRMT | |
| SCHEMBL18636492 | 0.91 | POLRMT (0.43) | TMPRSS2POLRMT | |
| SCHEMBL26213503 | 0.85 | TMPRSS2 (0.38) | TMPRSS2POLRMT | |
| SCHEMBL23960380 | 0.85 | POLRMT (0.37) | POLRMT | |
| SCHEMBL20144176 | 0.84 | TMPRSS2 (0.41) | TMPRSS2POLRMT | |
| SCHEMBL30423231 | 0.84 | TMPRSS2 (0.44) | TMPRSS2POLRMT | |
| SCHEMBL24407297 | 0.83 | TMPRSS2 (0.36) | TMPRSS2 | |
| SCHEMBL21283685 | 0.83 | POLRMT (0.43) | TMPRSS2POLRMT | |
| SCHEMBL18636613 | 0.82 | TMPRSS2 (0.35) | TMPRSS2POLRMT | |
| SCHEMBL24606302 | 0.82 | TMPRSS2 (0.38) | TMPRSS2POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355649-A1 | FORMULATIONS OF ANTI-VIRAL COMPOUNDS | SAYVAA PHARMACEUTICALS INC. | 2023-11-09 | — | — | US | disclosed |
| US-10251898-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2019-04-09 | — | — | US | disclosed |
| US-9724360-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2017-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355649-A1 | FORMULATIONS OF ANTI-VIRAL COMPOUNDS | SARS1, RNMT, NSUN2 | TMPRSS2 1436/4885POLRMT 53/4885 |
| US-10251898-B2 | Methods for treating Filoviridae virus infections | PNP, PRPF4, RPIA | TMPRSS2 1951/4885POLRMT 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.