Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23034577 | 0.93 | POLRMT (0.42) | POLRMT | |
| SCHEMBL19223089 | 0.91 | POLRMT (0.45) | POLRMT | |
| SCHEMBL20078640 | 0.86 | RIPK1 (0.33) | POLRMT | |
| SCHEMBL26944643 | 0.85 | POLRMT (0.31) | POLRMT | |
| SCHEMBL19223072 | 0.85 | TMPRSS2 (0.39) | POLRMT | |
| SCHEMBL18636442 | 0.83 | POLRMT (0.32) | POLRMT | |
| SCHEMBL24158262 | 0.83 | POLRMT (0.32) | POLRMT | |
| SCHEMBL26944644 | 0.83 | POLRMT (0.30) | POLRMT | |
| SCHEMBL26200503 | 0.83 | RIPK1 (0.32) | POLRMT | |
| SCHEMBL25973237 | 0.83 | FGFR1 (0.35) | POLRMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248753-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-08-10 | — | — | US | disclosed |
| US-11701372-B2 | Inhalation formulations of 1'-cyano substituted carba-nucleoside analogs | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210346288-A1 | PHARMACEUTICAL FORMULATION CONTAINING ACTIVE METABOLITES OF REMDESIVIR FOR INHALATION | Huang, Cai Gu (US) | 2021-11-11 | — | — | US | disclosed |
| US-20210330685-A1 | INHALATION FORMULATIONS OF 1'-CYANO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS | GILEAD SCIENCES, INC. | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210346288-A1 | PHARMACEUTICAL FORMULATION CONTAINING ACTIVE METABOLITES OF REMDESIVIR FOR INHALATION | RNMT, METTL3, METTL16 | POLRMT 28/4885 |
| US-20230248753-A1 | PHOSPHOLIPID COMPOUNDS AND USES THEREOF | PHOSPHO1, SGMS2, SGMS1 | POLRMT 361/4885 |
| US-20210330685-A1 | INHALATION FORMULATIONS OF 1'-CYANO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS | SLC29A1, SLC28A1, SLC29A2 | POLRMT 75/4885 |
| US-11701372-B2 | Inhalation formulations of 1'-cyano substituted carba-nucleoside analogs | SLC29A1, SLC28A1, SLC29A2 | POLRMT 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.