Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL18730213 | 0.87 | — | — | |
| Phosphine SCHEMBL19463355 | 0.87 | — | — | |
| SCHEMBL11694371 | 0.82 | — | — | |
| SCHEMBL6239687 | 0.82 | — | — | |
| SCHEMBL9778052 | 0.82 | — | — | |
| SCHEMBL11674077 | 0.82 | — | — | |
| SCHEMBL7042759 | 0.82 | — | — | |
| SCHEMBL8663059 | 0.82 | — | — | |
| SCHEMBL5067686 | 0.82 | — | — | |
| SCHEMBL10576947 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289534-B2 | Biocompatible composite and its use | PURAC BIOCHEM BV (NL) | 2016-03-22 | — | — | US | disclosed |
| US-20120040015-A1 | BIOCOMPATIBLE COMPOSITE AND ITS USE | PURAC BIOCHEM BV (NL) | 2012-02-16 | — | — | US | disclosed |
| EP-2243500-B1 | Biocompatible composite and its use | VIVOXID OY (FI) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010122098-A2 | BIOCOMPATIBLE COMPOSITE AND ITS USE | VIVOXID OY (FI) | 2010-10-28 | — | — | WO | disclosed |
| EP-2243500-A1 | Biocompatible composite and its use | Vivoxid Oy (FI) | 2010-10-27 | — | — | EP | disclosed |