Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165231 | 0.79 | SNCA (0.32) | DGAT1SNCA | |
| SCHEMBL1920711 | 0.72 | GBA1 (0.44) | DGAT1HSD17B10ALDH1A1KDM4EHPGD | |
| SCHEMBL1180748 | 0.71 | TTK (0.37) | DGAT1SNCA | |
| SCHEMBL2099862 | 0.71 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL4165224 | 0.70 | CXCR4 (0.34) | DGAT1KDM4EHPGDRAB9ASNCA | |
| SCHEMBL5624405 | 0.67 | LIPG (0.42) | DGAT1 | |
| SCHEMBL31081894 | 0.67 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL1922368 | 0.67 | PDCD1 (0.31) | — | |
| SCHEMBL14674020 | 0.65 | SNCA (0.36) | RAB9ASNCA | |
| SCHEMBL17593398 | 0.64 | FFAR4 (0.40) | SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | disclosed |