SCHEMBL2099862

SCHEMBL2099862

CC1(C)COB(c2ccc(CN(C(=O)O)C(C)(C)C)nc2)OC1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4165231 0.76 SNCA (0.32) DGAT1
SCHEMBL22366438 0.73 MEN1 (0.39) HDAC6
SCHEMBL1922366 0.71 DGAT1 (0.33) DGAT1
SCHEMBL2099348 0.71 ALDH1A1 (0.41)
SCHEMBL1180748 0.70 TTK (0.37) DGAT1
SCHEMBL1283942 0.69 DGAT1 (0.44) DGAT1
SCHEMBL2099860 0.68 DGAT1 (0.34) DGAT1
SCHEMBL20479676 0.68 CACNA1H (0.32)
SCHEMBL14674020 0.66 SNCA (0.36)
SCHEMBL22366419 0.65 CYP1A2 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163928-B2 Heteroaryl substituted benzothiazoles ASTRAZENECA AB (SE) 2012-04-24 US disclosed