Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157652 | 0.86 | NPC1 (0.38) | ALDH1A1RAB9A | |
| SCHEMBL20724194 | 0.84 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL19220549 | 0.83 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL19225348 | 0.75 | ALDH1A1 (0.36) | ALDH1A1LMNAMEN1KMT2APOLB | |
| SCHEMBL20724196 | 0.74 | MPO (0.38) | ALDH1A1LMNAKMT2APOLBRAB9A | |
| SCHEMBL20724198 | 0.73 | GABRB3 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL19157860 | 0.70 | ALDH1A1 (0.40) | ALDH1A1LMNARAB9A | |
| SCHEMBL19157898 | 0.68 | IDO1 (0.42) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL19220548 | 0.67 | ALDH1A1 (0.38) | ALDH1A1KMT2ARAB9A | |
| SCHEMBL20340997 | 0.66 | KMT2A (0.39) | ALDH1A1LMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10011613-B2 | Polycyclic pyridone derivative having integrase inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2018-07-03 | — | — | US | disclosed |
| US-20170226128-A1 | POLYCYCLIC PYRIDONE DERIVATIVE HAVING INTEGRASE INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10011613-B2 | Polycyclic pyridone derivative having integrase inhibitory activity | TYMP, CDK6, IMPA1 | ALDH1A1 1332/4885LMNA 1344/4885MEN1 4120/4885 |
| US-20170226128-A1 | POLYCYCLIC PYRIDONE DERIVATIVE HAVING INTEGRASE INHIBITORY ACTIVITY | TYMP, CDK6, IMPA1 | ALDH1A1 1332/4885LMNA 1344/4885MEN1 4120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.