Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15776314 | 0.81 | BRD4 (0.37) | SCN9ACNR2RIPK1PDE4BPDE4A | |
| SCHEMBL19225529 | 0.72 | RIPK1 (0.37) | SCN9ARIPK1PDE4BPDE4APDE4D | |
| SCHEMBL981699 | 0.71 | TDP1 (0.46) | RIPK1PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL983839 | 0.69 | TDP1 (0.47) | RIPK1PDE4BPDE4APDE4DPDE4C | |
| SCHEMBL9896972 | 0.68 | SCN9A (0.36) | SCN9ACNR2RIPK1 | |
| SCHEMBL983640 | 0.67 | CYP1A2 (0.51) | TDP1 | |
| SCHEMBL16653248 | 0.67 | CNR2 (0.46) | SCN9ACNR2RIPK1PDE4BPDE4A | |
| SCHEMBL983574 | 0.67 | EGFR (0.39) | PDE4BPDE4D | |
| SCHEMBL15871 | 0.67 | HTR2A (0.40) | CNR2PDE4BPDE4D | |
| SCHEMBL23915570 | 0.66 | CNR2 (0.39) | SCN9ACNR2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928867-B1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2017-08-09 | — | — | EP | disclosed |