Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.34 |
| ▸ | SAT1 | P21673 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromoacetal SCHEMBL103234 | 0.73 | — | — | |
| SCHEMBL25644246 | 0.71 | TSHR (0.45) | CYP2C19CYP1A2MEN1GLAKMT2A | |
| Bromoacetal SCHEMBL11383920 | 0.71 | THRB (0.42) | — | |
| SCHEMBL27929925 | 0.70 | DNM1 (0.54) | GLATSHRHTT | |
| SCHEMBL28800989 | 0.69 | DNM1 (0.47) | GLATSHRHTT | |
| SCHEMBL13492945 | 0.68 | CYP2C19 (0.55) | CYP2C19CYP1A2MEN1GLAKMT2A | |
| SCHEMBL13185663 | 0.68 | CYP2C19 (0.38) | CYP2C19CYP1A2MEN1GLAKMT2A | |
| SCHEMBL15442502 | 0.67 | CYP2C19 (0.60) | CYP2C19CYP1A2MEN1GLAKMT2A | |
| SCHEMBL27577082 | 0.67 | CYP2C19 (0.35) | CYP2C19CYP1A2MEN1GLAKMT2A | |
| SCHEMBL12380906 | 0.66 | CYP2C19 (0.52) | CYP2C19CYP1A2MEN1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847186-B1 | SUBSTITUTED AMINOQUINAZOLINES USEFUL AS KINASES INHIBITORS | TELIGENE LTD (CN) | 2017-08-09 | — | — | EP | disclosed |