Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 12/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225866 | 0.86 | CFD (0.40) | CFDF2PLGF11F7 | |
| SCHEMBL19225882 | 0.85 | CFD (0.40) | CFDF2 | |
| SCHEMBL19226057 | 0.80 | CFD (0.57) | CFD | |
| SCHEMBL19160079 | 0.79 | CFD (0.41) | CFDF2PLGF11F7 | |
| SCHEMBL19158750 | 0.79 | CFD (0.40) | CFDF2PLGF11F7 | |
| SCHEMBL19225888 | 0.78 | CFD (0.38) | CFD | |
| SCHEMBL19225872 | 0.78 | CFD (0.42) | CFD | |
| SCHEMBL19234486 | 0.77 | CFD (0.43) | CFD | |
| SCHEMBL19234177 | 0.77 | CFD (0.41) | CFD | |
| SCHEMBL19225941 | 0.76 | CFD (0.42) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |