Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225941 | 0.92 | CFD (0.42) | CFD | |
| SCHEMBL19225866 | 0.90 | CFD (0.40) | CFD | |
| SCHEMBL19225958 | 0.85 | CFD (0.40) | CFDNPC1RAB9A | |
| SCHEMBL15602038 | 0.79 | CFD (0.40) | CFDNPC1RAB9A | |
| SCHEMBL15602110 | 0.78 | CFD (0.58) | CFD | |
| SCHEMBL19225833 | 0.78 | CFD (0.41) | CFD | |
| SCHEMBL19225838 | 0.76 | CFD (0.39) | CFD | |
| SCHEMBL15602099 | 0.75 | CFD (0.57) | CFD | |
| SCHEMBL19158750 | 0.74 | CFD (0.40) | CFD | |
| SCHEMBL19225883 | 0.73 | F2 (0.42) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |