Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 16/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225838 | 0.93 | CFD (0.39) | DPP4PREPFAPF2CFD | |
| SCHEMBL19225952 | 0.91 | CFD (0.41) | DPP4FAPF2CFDPRSS1 | |
| SCHEMBL19225883 | 0.89 | F2 (0.42) | PREPFAPF2CFDPRSS1 | |
| SCHEMBL19225902 | 0.88 | CFD (0.39) | DPP4F2CFDPRSS1 | |
| SCHEMBL19225958 | 0.86 | CFD (0.40) | DPP4F2CFDPRSS1 | |
| SCHEMBL19226064 | 0.86 | CFD (0.40) | DPP4PREPFAPF2CFD | |
| SCHEMBL19226083 | 0.84 | CFD (0.39) | F2CFDPRSS1 | |
| SCHEMBL19225895 | 0.84 | CFD (0.40) | PREPF2CFDPRSS1 | |
| SCHEMBL19225967 | 0.84 | CFD (0.40) | PREPF2CFDPRSS1 | |
| SCHEMBL19226078 | 0.84 | CFD (0.46) | FAPF2CFDPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |