Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 14/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230512 | 0.92 | NR1H4 (0.37) | FAAHITGB3ITGA2B | |
| SCHEMBL19230586 | 0.86 | FAAH (0.33) | FAAHITGB3ITGA2BADRB1ADRB3 | |
| SCHEMBL19230369 | 0.85 | ITGB3 (0.36) | FAAHKMT2AITGB3ITGA2BTAS1R3 | |
| SCHEMBL19230598 | 0.85 | FAAH (0.34) | FAAHKMT2A | |
| SCHEMBL19230321 | 0.84 | KMT2A (0.40) | FAAHKMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19230657 | 0.80 | SLC8A1 (0.36) | ITGB3ITGA2B | |
| SCHEMBL19230377 | 0.80 | SLC8A1 (0.37) | ITGB3ITGA2B | |
| SCHEMBL19230762 | 0.80 | MAPT (0.38) | KMT2AADRB3 | |
| SCHEMBL19230764 | 0.79 | SLC8A1 (0.40) | — | |
| SCHEMBL19202445 | 0.79 | NR1H4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |