Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230756 | 0.92 | ITGB3 (0.38) | ITGB3ITGA2BNR1H4NPC1RAB9A | |
| SCHEMBL19230576 | 0.86 | ITGB3 (0.35) | ITGB3ITGA2B | |
| SCHEMBL19230320 | 0.85 | FAAH (0.38) | ITGB3ITGA2BFAAHKMT2ATAS1R3 | |
| SCHEMBL19230598 | 0.82 | FAAH (0.34) | FAAHNR1H4LMNATP53ALDH1A1 | |
| SCHEMBL19230657 | 0.79 | SLC8A1 (0.36) | ITGB3ITGA2B | |
| SCHEMBL19230377 | 0.79 | SLC8A1 (0.37) | ITGB3ITGA2BNR1H4 | |
| SCHEMBL19230764 | 0.78 | SLC8A1 (0.40) | — | |
| SCHEMBL19230784 | 0.77 | SLC8A1 (0.36) | ITGB3ITGA2B | |
| SCHEMBL19230677 | 0.76 | FAAH (0.35) | FAAHRAB9ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL19230512 | 0.76 | NR1H4 (0.37) | ITGB3ITGA2BFAAHNR1H4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |