SCHEMBL19230366

SCHEMBL19230366

CN1C(=O)C(=O)c2cc3cc4ccccc4cc3cc21

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.56
TTR P02766 1/20 0.56
CASP3 P42574 7/20 0.50
CASP7 P55210 3/20 0.45
CASP1 P29466 1/20 0.45
CASP4 P49662 1/20 0.45
CASP9 P55211 1/20 0.45
CASP6 P55212 1/20 0.45
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
ILF3 Q12906 1/20 0.39
LMNA P02545 1/20 0.39
BCHE P06276 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19195513 0.79 CASP3 (0.52) CES1TTRCASP3MEN1ALDH1A1
SCHEMBL12552816 0.74 CASP3 (0.56) CES1TTRCASP3MEN1ALDH1A1
SCHEMBL6318641 0.73 CASP3 (0.52) CES1TTRCASP3CASP7CASP1
SCHEMBL12793285 0.73 AKT1 (0.43) CES1TTRCASP7CASP1ALDH1A1
SCHEMBL126628 0.72 CES1 (1.00) CES1TTRCASP3MEN1ALDH1A1
SCHEMBL12775944 0.72 ALDH1A1 (0.43) CES1TTRCASP3CASP7CASP1
SCHEMBL28252336 0.72 CES1 (1.00) CES1TTRCASP3MEN1ALDH1A1
SCHEMBL54876 0.71 MEN1 (0.50) CES1TTRCASP7CASP1MEN1
SCHEMBL10057987 0.71 MEN1 (0.50) CES1TTRCASP7CASP1MEN1
SCHEMBL2516264 0.71 MEN1 (0.50) CES1TTRCASP7CASP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017137142-A1 A POLYMER, COMPOSITION, FORMING SACRIFICIAL LAYER AND METHOD FOR SEMICONDUCTOR DEVICE THEREWITH AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2017-08-17 WO disclosed