Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | SLC8A1 | P32418 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230577 | 0.88 | KDM4E (0.44) | SLC8A1CA1CA2FFAR1ABCB11 | |
| SCHEMBL19230993 | 0.88 | ESR1 (0.47) | ESR2ESR1SLC8A1RAB9APDK1 | |
| SCHEMBL19230805 | 0.87 | ESR1 (0.49) | ESR2ESR1RAB9APDK1PDK2 | |
| SCHEMBL19230656 | 0.87 | ESR1 (0.49) | ESR2ESR1RAB9APDK1PDK2 | |
| SCHEMBL19230310 | 0.87 | ESR1 (0.49) | ESR2ESR1RAB9APDK1PDK2 | |
| SCHEMBL19230992 | 0.86 | ESR2 (0.44) | ESR2ESR1SLC8A1RAB9APDK1 | |
| SCHEMBL19230616 | 0.83 | ESR2 (0.65) | ESR2ESR1SLC8A1RAB9ACA12 | |
| SCHEMBL24102062 | 0.79 | CA12 (0.43) | SLC8A1RAB9APDK2CA12CA1 | |
| SCHEMBL19230370 | 0.79 | SLC8A1 (0.37) | ESR2ESR1SLC8A1RAB9ACHRNB2 | |
| SCHEMBL19230991 | 0.78 | SLC8A1 (0.43) | SLC8A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |