Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC8A1 | P32418 | 9/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230991 | 0.88 | SLC8A1 (0.43) | SLC8A1CA1CA2GABRA1GABRB2 | |
| SCHEMBL19230375 | 0.88 | ESR2 (0.46) | SLC8A1FFAR1CA1CA2ABCB11 | |
| SCHEMBL19230824 | 0.87 | NOTUM (0.43) | SLC8A1 | |
| SCHEMBL19230614 | 0.83 | ESR1 (0.50) | MAPTSLC8A1CA1CA2GABRA1 | |
| SCHEMBL24102062 | 0.78 | CA12 (0.43) | SLC8A1FFAR1CA1CA2ABCB11 | |
| SCHEMBL19230993 | 0.78 | ESR1 (0.47) | SLC8A1CA1CA2 | |
| SCHEMBL19230789 | 0.78 | ESR1 (0.39) | KDM4EALDH1A1TSHRSLC8A1FFAR1 | |
| SCHEMBL19230656 | 0.77 | ESR1 (0.49) | KDM4EALDH1A1MAPTTSHRCA1 | |
| SCHEMBL19230805 | 0.77 | ESR1 (0.49) | KDM4EALDH1A1MAPTTSHRCA1 | |
| SCHEMBL19230310 | 0.77 | ESR1 (0.49) | KDM4EALDH1A1MAPTTSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |