Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18031703 | 1.00 | CA2 (0.40) | CA2MAPK1CA1SLC1A3SLC1A2 | |
| SCHEMBL15132427 | 1.00 | CA2 (0.40) | CA2MAPK1CA1SLC1A3SLC1A2 | |
| SCHEMBL21016297 | 0.93 | GPR84 (0.42) | CA2CA1SLC1A2SLC1A1FDPS | |
| SCHEMBL6871815 | 0.91 | GPR84 (0.45) | CA2FDPSGPR84FFAR1 | |
| SCHEMBL15132429 | 0.86 | TDP1 (0.44) | SLC1A3SLC1A2SLC1A1ALDH1A1FDPS | |
| SCHEMBL19230440 | 0.86 | TDP1 (0.44) | SLC1A3SLC1A2SLC1A1ALDH1A1FDPS | |
| SCHEMBL19230441 | 0.86 | TDP1 (0.44) | SLC1A3SLC1A2SLC1A1ALDH1A1FDPS | |
| SCHEMBL19577891 | 0.83 | CA2 (0.38) | CA2MAPK1CA1SLC1A3SLC1A2 | |
| SCHEMBL2512194 | 0.82 | CA2 (0.50) | CA2MAPK1CA1SLC1A3SLC1A2 | |
| SCHEMBL16585650 | 0.82 | CA2 (0.50) | CA2MAPK1CA1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136708-A1 | SYNTHESIS AND COMPOSITION OF RAPAFUCIN LIBRARIES | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-10 | — | — | WO | disclosed |