Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016297 | 0.98 | GPR84 (0.42) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL18031703 | 0.91 | CA2 (0.40) | GPR84FFAR1CA2FDPS | |
| SCHEMBL15132427 | 0.91 | CA2 (0.40) | GPR84FFAR1CA2FDPS | |
| SCHEMBL19230435 | 0.91 | CA2 (0.40) | GPR84FFAR1CA2FDPS | |
| SCHEMBL5530871 | 0.83 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL3852448 | 0.83 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL308689 | 0.83 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL18221941 | 0.83 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL351779 | 0.83 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL3116423 | 0.83 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983995-B1 | Pharmaceutically-active dimethyl-(3-aryl-but-3-enyl)-amine compounds | GRUENENTHAL GMBH (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1069106-B1 | Dimethyl-(3-aryl-but-3-enyl) amine derivatives with analgesic activity | GRUENENTHAL GMBH (DE) | 2004-01-28 | — | — | EP | claimed |
| EP-0799819-B1 | 1-Dimethylaminomethyl 2-phenyl cycloalk-2-ene derivatives with analgesic activity | GRUENENTHAL GMBH (DE) | 2002-09-11 | — | — | EP | claimed |
| EP-0780369-B1 | 1-Phenyl-2-dimethylaminomethyl-cyclohexan-1-ol derivatives as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 2000-01-19 | — | — | EP | claimed |
| EP-0753506-B1 | 6-Dimethylaminomethyl-1-phenyl-cyclo-hexane compounds as pharmaceutical agents | GRUENENTHAL GMBH (DE) | 1999-08-18 | — | — | EP | claimed |
| EP-0693475-B1 | 1-Phenyl-3-dimethylamino-propane derivatives having pharmacological activity | GRUENENTHAL GMBH (DE) | 1998-02-11 | — | — | EP | claimed |