Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230513 | 0.92 | KDM4E (0.48) | AKR1C3ALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL19230582 | 0.83 | PDK1 (0.46) | AKR1C3ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL5519074 | 0.81 | DRD1 (0.54) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL19230510 | 0.81 | WDR5 (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL19230504 | 0.80 | MAOB (0.50) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL19230583 | 0.77 | PDK1 (0.49) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL2948505 | 0.76 | AKR1C3 (0.56) | AKR1C3KDM4EHDAC1HDAC6GFER | |
| SCHEMBL5518165 | 0.75 | DRD1 (0.50) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL19230514 | 0.74 | PDK1 (0.46) | AKR1C3ALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL3281251 | 0.72 | AKR1C3 (0.76) | AKR1C3LMNATAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-108602811-A | FXR receptor stimulating agents | 山东轩竹医药科技有限公司 | 2018-09-28 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |