Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230502 | 0.92 | AKR1C3 (0.52) | KDM4EAKR1C3GFERCHRM1MAPT | |
| SCHEMBL19230510 | 0.89 | WDR5 (0.49) | KDM4ETIPARPCHRM1MAPTCA1 | |
| SCHEMBL19230514 | 0.82 | PDK1 (0.46) | KDM4EAKR1C3CA1CA2ALDH1A1 | |
| SCHEMBL11286840 | 0.78 | TIPARP (0.50) | KDM4ETIPARPAKR1C3GFERMAPT | |
| SCHEMBL5519074 | 0.76 | DRD1 (0.54) | TIPARPMAPTLMNAALDH1A1NOTUM | |
| SCHEMBL19230596 | 0.75 | PDK1 (0.49) | KDM4EMAPTCA1CA2ALDH1A1 | |
| SCHEMBL2948505 | 0.73 | AKR1C3 (0.56) | KDM4EAKR1C3GFERCA1CA2 | |
| SCHEMBL19230582 | 0.73 | PDK1 (0.46) | KDM4EAKR1C3MAPTCA1CA2 | |
| SCHEMBL11284844 | 0.73 | MAPT (0.52) | KDM4ETIPARPAKR1C3MAPTLMNA | |
| SCHEMBL11281568 | 0.72 | TIPARP (0.46) | KDM4ETIPARPAKR1C3GFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |