Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29600453 | 0.80 | SLC6A3 (0.44) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL30548823 | 0.80 | SLC6A3 (0.44) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL24357853 | 0.80 | SLC6A3 (0.44) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL19230575 | 0.79 | SLC6A2 (0.41) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL19230646 | 0.79 | HSD11B1 (0.36) | HSD11B1ALDH1A1SMN1; SMN2SLC6A3SLC6A2 | |
| SCHEMBL31379004 | 0.77 | SLC6A3 (0.42) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL23528113 | 0.77 | SLC6A3 (0.42) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL23551037 | 0.77 | SLC6A3 (0.42) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL24429131 | 0.76 | SLC6A2 (0.39) | ALDH1A1ATMSMN1; SMN2NPSR1SLC6A3 | |
| SCHEMBL19230649 | 0.75 | NPC1 (0.37) | HSD11B1SMN1; SMN2SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |