Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230285 | 0.90 | ESR2 (0.57) | ESR2ESR1 | |
| SCHEMBL19230671 | 0.81 | ESR2 (0.50) | ESR2ESR1PTPN1CHRNA7 | |
| SCHEMBL19230672 | 0.78 | ESR2 (0.46) | ESR2ESR1PTPN1 | |
| SCHEMBL4366876 | 0.77 | ESR2 (0.61) | ESR2ESR1 | |
| SCHEMBL1447356 | 0.76 | ESR2 (0.68) | ESR2ESR1PTPN1CHRNA7 | |
| SCHEMBL30058248 | 0.76 | ESR2 (0.68) | ESR2ESR1PTPN1CHRNA7 | |
| SCHEMBL19230314 | 0.75 | TTR (0.59) | ESR2PTPN1 | |
| SCHEMBL28649906 | 0.74 | ESR1 (0.53) | ESR2ESR1 | |
| SCHEMBL19230545 | 0.74 | ESR1 (0.53) | ESR2ESR1 | |
| SCHEMBL19230284 | 0.73 | AR (0.66) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |