Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230794 | 0.88 | MAPT (0.42) | DRD2DRD1DRD4DRD5WDR5 | |
| SCHEMBL19230798 | 0.86 | PDK2 (0.38) | WDR5GRM1PDK2PDK4PDK1 | |
| SCHEMBL19230651 | 0.84 | ALDH1A1 (0.59) | WDR5MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19230583 | 0.77 | PDK1 (0.49) | WDR5GRM1PDK2PDK4PDK1 | |
| SCHEMBL22859092 | 0.74 | PRMT5 (0.47) | MEN1PRMT5KMT2AWDR77LMNA | |
| SCHEMBL19230596 | 0.73 | PDK1 (0.49) | WDR5PDK2PDK4PDK1PDK3 | |
| SCHEMBL5299350 | 0.72 | PDGFRB (0.48) | SYKHDAC11KDRPDGFRBACHE | |
| SCHEMBL21381399 | 0.72 | SYK (0.43) | SYKHDAC11KDRALDH1A1 | |
| SCHEMBL6369762 | 0.71 | PRMT5 (0.52) | MEN1PRMT5KMT2AWDR77KDM4E | |
| SCHEMBL5516095 | 0.71 | ESR2 (0.50) | DRD2DRD1DRD4DRD5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |