Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.59 |
| ▸ | LMNA | P02545 | 8/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | WDR5 | P61964 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247139 | 0.88 | ALDH1A1 (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL19230796 | 0.84 | DRD2 (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL19230794 | 0.83 | MAPT (0.42) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3025176 | 0.77 | MAPT (0.68) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL222270 | 0.71 | TDP1 (0.67) | ALDH1A1MAPTSMN1; SMN2MAPK1HTT | |
| SCHEMBL19230798 | 0.71 | PDK2 (0.38) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL22859092 | 0.70 | PRMT5 (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL4159162 | 0.70 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPTSMN1; SMN2HTT | |
| SCHEMBL4540125 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL27927947 | 0.69 | ALDH1A1 (0.76) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |