Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118472 | 0.83 | KDM4E (0.39) | ALDH1A1BLMSMN1; SMN2KDM4EGAA | |
| SCHEMBL4348692 | 0.82 | ADRA1D (0.37) | CYP1A2MEN1KMT2ABRD4TAF1 | |
| SCHEMBL6864608 | 0.80 | TDP1 (0.44) | ALDH1A1TSHRADORA2APDE4APDE4B | |
| SCHEMBL8656963 | 0.79 | ALDH1A1 (0.45) | CYP1A2MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL8952367 | 0.79 | ADRA1D (0.33) | CYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL7099892 | 0.79 | ADORA2A (0.47) | ALDH1A1CYP3A4TSHRKDM4EGAA | |
| SCHEMBL8377755 | 0.78 | TYMP (0.32) | — | |
| SCHEMBL10618040 | 0.78 | ADRA1D (0.33) | — | |
| SCHEMBL8377767 | 0.78 | ADRA1D (0.31) | — | |
| SCHEMBL4372132 | 0.78 | CCR8 (0.32) | KMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
| WO-2022012798-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-01-20 | — | — | WO | disclosed |
| US-10378011-B2 | Oligonucleotide | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2019-08-13 | — | — | US | disclosed |
| CN-109715802-A | Oligonucleotide probe and use thereof | 卡里斯科学公司 | 2019-05-03 | — | — | CN | disclosed |
| WO-2017214145-A1 | METHODS FOR DETECTING OLIGONUCLEOTIDES IN A SAMPLE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-14 | — | — | WO | disclosed |
| CN-106661611-A | Method for detecting Trichomonas vaginalis | 西菲伊德公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20150376611-A1 | OLIGONUCLEOTIDE | KYOWA KIRIN CO., LTD. (JP) | 2015-12-31 | — | — | US | disclosed |
| CN-101450954-B | Nucleotide analogs and use thereof, and medicament composition containing nucleotide analogs | UNIV PLA 2ND MILITARY MEDICAL | 2013-05-08 | — | — | CN | disclosed |
| EP-2576786-A1 | HIGH-AFFINITY NUCLEIC ACID APTAMERS AGAINST SCLEROSTIN PROTEIN | The University of Hong Kong (CN) | 2013-04-10 | — | — | EP | disclosed |
| CN-1436082-A | 3 '-or 2' -hydroxymethyl substituted nucleoside derivatives for the treatment of hepatitis virus infections | PHARMASSET LTD (BB) | 2003-08-13 | — | — | CN | disclosed |
| US-6268373-B1 | ENZYME INHIBITORS | EURO-CELTIQUE S.A. (LU) | 2001-07-31 | — | — | US | disclosed |
| US-6025361-A | EFFECTIVE PDE IV INHIBITORS, ASTHMA | EURO-CELTIQUE, S.A. (LU) | 2000-02-15 | — | — | US | disclosed |
| US-5977119-A | Trisubstituted thioxanthines | EURO-CELTIQUE, S.A. (LU) | 1999-11-02 | — | — | US | disclosed |
| EP-0799040-A4 | TRISUBSTITUTED THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | disclosed |
| EP-0799040-A1 | TRISUBSTITUTED THIOXANTHINES | Euroceltique S.A. (LU) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996018400-A1 | TRISUBSTITUTED THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |
| US-RE34201-E | Analgesics | ANAQUEST, INC. (US) | 1993-03-23 | — | — | US | disclosed |
| US-5053411-A | Analgesics | ANAQUEST, INC. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0396282-A2 | N-aryl-N-[4-(heterocyclicalkyl) piperidinyl]amides and pharmaceutical compositions and methods employing such compounds | BOC, INC. (US) | 1990-11-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10378011-B2 | Oligonucleotide | HNRNPA3, AGO2, RBM3 | CYP1A2 4285/4885MEN1 3657/4885KMT2A 464/4885 |
| US-20230273456-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6D, PDE6A | CYP1A2 2773/4885MEN1 3047/4885KMT2A 3838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.