SCHEMBL1923353

SCHEMBL1923353

CC(C)(C)C1(C(C)(C)C)c2cc(Cl)ccc2-c2ccc(Cl)cc21

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 4/20 0.52
AKR1B1 P15121 3/20 0.42
AKR1A1 P14550 2/20 0.42
PPOX P50336 1/20 0.38
S100A4 P26447 2/20 0.37
CES1 P23141 1/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
AHR P35869 1/20 0.33
PGR P06401 1/20 0.33
HSD11B1 P28845 1/20 0.33
METAP1 P53582 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1921129 0.91 PDK2 (0.54) PDK2AKR1B1AKR1A1S100A4
SCHEMBL1922755 0.75 PDK2 (0.52) PDK2AKR1B1AKR1A1PPOXS100A4
SCHEMBL1922096 0.74 PDK2 (0.44) PDK2AKR1B1AKR1A1S100A4CES1
SCHEMBL1921479 0.74 TDP2 (0.35) CES1
SCHEMBL24406657 0.72 PDK2 (0.46) PDK2AKR1B1AKR1A1
SCHEMBL16435208 0.71 PDK2 (0.48) PDK2AKR1B1AKR1A1PPOXS100A4
SCHEMBL25134633 0.71 PDK2 (0.59) PDK2AKR1B1AKR1A1PPOXS100A4
SCHEMBL1921866 0.70 PDK2 (0.47) PDK2AKR1B1AKR1A1PPOXS100A4
SCHEMBL1921508 0.70 PDK2 (0.47) PDK2AKR1B1AKR1A1PPOXS100A4
SCHEMBL19977174 0.68 PDK2 (0.46) PDK2AKR1B1AKR1A1PPOXS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed