SCHEMBL1922096

SCHEMBL1922096

CC(C)(C)C1(C(C)(C)C)c2cc(Br)ccc2-c2ccc(Br)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.44
S100A4 P26447 1/20 0.37
AKR1A1 P14550 1/20 0.36
AKR1B1 P15121 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
TDP2 O95551 1/20 0.35
METAP1 P53582 1/20 0.32
PTPRC P08575 1/20 0.32
ADRA2A P08913 1/20 0.32
PNMT P11086 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
BCL2 P10415 1/20 0.31
MCL1 Q07820 1/20 0.31
KDM1A O60341 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1923391 0.91 PDK2 (0.54) PDK2PTPRCALDH1A1
SCHEMBL17430723 0.75 PDK2 (0.44) PDK2S100A4AKR1A1AKR1B1CA1
SCHEMBL19116324 0.75 PDK2 (0.44) PDK2S100A4AKR1A1AKR1B1CA1
SCHEMBL29403081 0.75 PDK2 (0.44) PDK2S100A4AKR1A1AKR1B1CA1
SCHEMBL204806 0.75 PDK2 (0.44) PDK2S100A4AKR1A1AKR1B1CA1
SCHEMBL29587737 0.75 PDK2 (0.44) PDK2S100A4AKR1A1AKR1B1CA1
SCHEMBL1921479 0.74 TDP2 (0.35) TDP2TGM2CES1
SCHEMBL1923353 0.74 PDK2 (0.52) PDK2S100A4AKR1A1AKR1B1METAP1
SCHEMBL29404184 0.74 PDK2 (0.47) PDK2S100A4AKR1A1AKR1B1CA1
SCHEMBL437007 0.74 PDK2 (0.47) PDK2S100A4AKR1A1AKR1B1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed