Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715719 | 0.88 | SPHK1 (0.59) | SPHK1SPHK2S1PR1S1PR3S1PR4 | |
| SCHEMBL19234500 | 0.88 | S1PR1 (0.60) | CRHBPCRHR2SPHK1SPHK2SRC | |
| SCHEMBL19375764 | 0.86 | SPHK1 (0.49) | SPHK1SPHK2S1PR1S1PR3LTA4H | |
| SCHEMBL370590 | 0.85 | CRHBP (0.59) | CRHBPCRHR2SPHK1SPHK2SRC | |
| SCHEMBL20715718 | 0.85 | GAA (0.55) | CRHBPCRHR2SPHK1SPHK2SMN1; SMN2 | |
| SCHEMBL19234507 | 0.85 | SPHK1 (0.53) | CRHBPCRHR2SPHK1SPHK2SRC | |
| SCHEMBL19234512 | 0.84 | SPHK1 (0.69) | CRHBPCRHR2SPHK1SPHK2SRC | |
| Hydrochloric Acid SCHEMBL21724241 | 0.82 | LTA4H (0.51) | SPHK1SPHK2S1PR1S1PR3RAB9A | |
| Hydrochloric Acid SCHEMBL21724243 | 0.82 | LTA4H (0.51) | SPHK1SPHK2S1PR1S1PR3RAB9A | |
| SCHEMBL6291030 | 0.81 | LTA4H (0.45) | SPHK1SPHK2S1PR1S1PR3LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136943-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2017-08-17 | — | — | WO | disclosed |