Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.46 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20715665 | 0.88 | LTA4H (0.56) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL20715888 | 0.86 | GAA (0.56) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL20715657 | 0.85 | SPHK1 (0.62) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL19234502 | 0.85 | CRHBP (0.51) | CRHBPCRHR2SMN1; SMN2AAK1SPHK1 | |
| SCHEMBL19375764 | 0.83 | SPHK1 (0.49) | CA12CA1CA2AAK1SPHK1 | |
| SCHEMBL20715719 | 0.82 | SPHK1 (0.59) | SPHK1SPHK2 | |
| SCHEMBL20715658 | 0.81 | LTA4H (0.60) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL20715478 | 0.80 | MAPT (0.58) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL20715479 | 0.80 | MAPT (0.58) | GAAMAPTCRHBPCRHR2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21724241 | 0.80 | LTA4H (0.51) | SMN1; SMN2AAK1SPHK1LARS1CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220112242-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2022-04-14 | — | — | US | disclosed |
| US-11279732-B2 | Somatostatin receptor antagonist compounds and methods of using the same | CDRD VENTURES INC. (CA) | 2022-03-22 | — | — | US | disclosed |
| US-20190040102-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279732-B2 | Somatostatin receptor antagonist compounds and methods of using the same | GPR119, SSTR5, SSTR2 | GAA 260/4885MAPT 4302/4885CRHBP 259/4885 |
| US-20220112242-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | GPR119, SSTR5, SSTR2 | GAA 265/4885MAPT 4276/4885CRHBP 260/4885 |
| US-20190040102-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | GPR119, SSTR5, SSTR2 | GAA 260/4885MAPT 4302/4885CRHBP 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.