Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrimidine SCHEMBL28155909 | 0.79 | CYP3A4 (0.42) | ALDH1A1KDM4EHTT | |
| SCHEMBL28451160 | 0.78 | ALDH1A1 (0.45) | ALDH1A1KDM4EGLAHTTSMN1; SMN2 | |
| SCHEMBL8252 | 0.76 | CYP3A4 (0.52) | ALDH1A1KDM4EHTT | |
| Bromide SCHEMBL28406943 | 0.74 | CYP3A4 (0.50) | ALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL27904367 | 0.74 | MAPT (0.56) | GAAALDH1A1KDM4EHTT | |
| SCHEMBL6880437 | 0.74 | CHRM2 (0.47) | GAAALDH1A1KDM4EPOLBHTT | |
| SCHEMBL178473 | 0.73 | — | — | |
| SCHEMBL6077220 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1KDM4EHTTSMN1; SMN2RAB9A | |
| SCHEMBL3971719 | 0.73 | LMNA (0.52) | GAAHTTLMNA | |
| SCHEMBL29196305 | 0.73 | MEN1 (0.52) | GAAKDM4EGLARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136395-A1 | BENZOPYRAZOLE COMPOUNDS AND ANALOGUES THEREOF | BIOCRYST PHARMACEUTICALS, INC. (US) | 2017-08-10 | — | — | WO | disclosed |