SCHEMBL8252

SCHEMBL8252

CONCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
IDO1 P14902 2/20 0.48
THRB P10828 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HTT P42858 2/20 0.44
SIGMAR1 Q99720 1/20 0.43
CA2 P00918 2/20 0.43
ADH1B P00325 1/20 0.43
ADH1C P00326 1/20 0.43
ADH1A P07327 1/20 0.43
ADH7 P40394 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
ALOX12 P18054 1/20 0.43
CA12 O43570 1/20 0.43
CA7 P43166 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28406943 0.98 CYP3A4 (0.50) CYP3A4MAPTKDM4EIDO1THRB
Naphthalene SCHEMBL9463547 0.93 CYP3A4 (0.46) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL28377529 0.91 CYP3A4 (0.45) CYP3A4MAPTKDM4EIDO1THRB
Benzaldehyde SCHEMBL8037478 0.84 ALDH1A1 (0.50) CYP3A4MAPTKDM4EMEN1KMT2A
Chlorobenzene SCHEMBL28378842 0.83 SIGMAR1 (0.41) CYP3A4MAPTKDM4EMEN1KMT2A
SCHEMBL7955870 0.81 SIGMAR1 (0.50) CYP3A4MAPTKDM4EIDO1THRB
Trifluoromethanesulfonic Acid SCHEMBL3921319 0.80 HTT (0.43) MAPTHTTCA2ALDH1A1CA12
SCHEMBL11661655 0.79 IDO1 (0.52) CYP3A4MAPTKDM4EIDO1THRB
SCHEMBL6880437 0.78 CHRM2 (0.47) MAPTKDM4EIDO1THRBMEN1
SCHEMBL5179520 0.78 CYP3A4 (0.45) CYP3A4MAPTKDM4EIDO1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118806962-B Enzyme-responsive antibacterial hydrogel coating modified medical gauze and preparation method thereof 浙江大学 2025-03-18 CN claimed
CN-119595788-A Biomarker method for predicting curative effect of cyclosporine on aplastic anemia 宜兴市人民医院 2025-03-11 CN claimed
CN-118806962-A Enzyme-responsive antibacterial hydrogel coating modified medical gauze and preparation method thereof 浙江大学 2024-10-22 CN claimed
CN-118557747-A Conjugates of cell binding molecules and camptothecin analogs 杭州多禧生物科技有限公司 2024-08-30 CN claimed
US-12024483-B2 Synthesis method of hydroxybenzylamine TAIZHOU CHUANGYUAN INDUSTRIAL TECHNOLOGY CO., LTD (CN) 2024-07-02 US claimed
CN-117187133-A Culture medium for helicobacter pylori separation culture 苏州长柏生物科技有限公司 2023-12-08 CN claimed
CN-114105983-B Preparation and application of chiral 1,4,7, 10-tetraaza-2, 6-pyridine cycloparaffin derivative and metal chelate thereof 国科温州研究院(温州生物材料与工程研究所) 2023-08-11 CN claimed
CN-116082232-A Monoamine oxidase inhibitor, preparation method and application thereof 浙江海洋大学 2023-05-09 CN claimed
CN-115073373-A Method for asymmetric synthesis of (R) -5' -methoxy labdanin 广东嘉博制药有限公司 2022-09-20 CN claimed
US-20220289664-A1 SYNTHESIS METHOD OF HYDROXYBENZYLAMINE TAIZHOU CHUANGYUAN INDUSTRIAL TECHNOLOGY CO., LTD (CN) 2022-09-15 US claimed
WO-1996018391-A2 USE OF MONO AND BICARBOXYLIC ACID AMIDES FOR THE MANUFACTURE OF A MEDICAMENT ACTIVE AT THE PERIPHERAL CANNABINOID RECEPTOR LIFEGROUP S.P.A. (IT) 1996-06-20 WO claimed
EP-0672646-A1 Process for producing beta-nitro-enamines and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-09-20 EP claimed
WO-1994000432-A1 ANORECTIC EPINEPHRINE DERIVATIVES THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1994-01-06 WO claimed
EP-0563145-A1 CHELATING AGENTS NYCOMED AS (NO) 1993-10-06 EP claimed
WO-1992011232-A1 CHELATING AGENTS NYCOMED IMAGING AS (NO) 1992-07-09 WO claimed
US-4880840-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1989-11-14 US claimed
US-4696964-A HEAT RESISTANCE, OXIDATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1987-09-29 US claimed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 US claimed
US-4268510-A DEMETHANIZATION, METABOLISM, RUMEN IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-05-19 US claimed
EP-0010348-A1 Heterocyclic trichloromethyl derivatives, process for their preparation and their use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-04-30 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12024483-B2 Synthesis method of hydroxybenzylamine HRH4, HRH2, HNMT CYP3A4 128/4885MAPT 3058/4885KDM4E 555/4885
US-20220289664-A1 SYNTHESIS METHOD OF HYDROXYBENZYLAMINE HRH4, HRH2, HNMT CYP3A4 128/4885MAPT 3058/4885KDM4E 555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.