SCHEMBL19237182

SCHEMBL19237182

c1ccc(-c2cccc(N(c3ccc(-c4cccc5c4oc4ccccc45)cc3)c3ccccc3-c3cccc4c3-c3ccccc3C43c4ccccc4-c4ccccc43)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.39
GGPS1 O95749 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.31
PRKDC P78527 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19237322 0.95 ALOX5 (0.40) ALOX5GGPS1PTGES2PRKDC
SCHEMBL23769797 0.95 ALOX5 (0.38) ALOX5GGPS1PTGES2PRKDC
SCHEMBL17690158 0.94 ALOX5 (0.40) ALOX5GGPS1PTGES2PRKDC
SCHEMBL22183170 0.93 ALOX5 (0.38) ALOX5GGPS1PTGES2PRKDC
SCHEMBL19237342 0.93 ALOX5 (0.40) ALOX5GGPS1PTGES2PRKDC
SCHEMBL19237158 0.93 ALOX5 (0.40) ALOX5GGPS1PTGES2PRKDC
SCHEMBL19010986 0.92 ALOX5 (0.36) ALOX5GGPS1PRKDC
SCHEMBL23770029 0.92 ALOX5 (0.40) ALOX5GGPS1PTGES2PRKDC
SCHEMBL19011167 0.92 ALOX5 (0.43) ALOX5GGPS1PTGES2PRKDC
SCHEMBL23769957 0.91 ALOX5 (0.35) ALOX5GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3411455-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-10-21 EP disclosed
US-20190040034-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-02-07 US disclosed
WO-2017133829-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-08-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190040034-A1 MATERIALS FOR ELECTRONIC DEVICES EFNA1, GPX1, EPX ALOX5 2944/4885GGPS1 1699/4885PTGES2 859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.