Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | F7 | P08709 | 2/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889885 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6884903 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL11739620 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6888186 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL2837452 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6891959 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL3652371 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6890958 | 0.97 | — | — | |
| SCHEMBL6067655 | 0.90 | — | — | |
| SCHEMBL7640627 | 0.80 | FAAH (0.54) | LMNAMAPTABCC4TERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349861-A1 | PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND SILICIC ACID ESTERS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE | Henkel AG & Co. KGaA (DE) | 2018-07-25 | — | — | EP | disclosed |
| WO-2017046052-A1 | PERFUME COMPOSITION COMPRISING FRAGRANCE MODULATOR COMPOUNDS AND SILICIC ACID ESTERS FOR INCREASING AND PROLONGING THE INTENSITY OF FRAGRANCE | HENKEL AG & CO. KGAA (DE) | 2017-03-23 | — | — | WO | disclosed |
| EP-1960454-B1 | POLYORGANOSILOXANE COMPOSITION FOR USE IN UNSATURATED ELASTOMER, ARTICLE MADE THEREFROM, AND ASSOCIATED METHOD | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2016-10-12 | — | — | EP | disclosed |
| US-8933195-B2 | Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments | NANJING YOKO BIOMEDICAL R & D LTD. (CN) | 2015-01-13 | — | — | US | disclosed |
| EP-1976911-B1 | POLYORGANOSILOXANE COMPOSITION, AND ASSOCIATED METHOD | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-10-01 | — | — | EP | disclosed |
| US-20140243501-A1 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | NANJING YOKO BIOMEDICAL R & D LTD. [CN/CN] (CN) | 2014-08-28 | — | — | US | disclosed |
| US-8084549-B2 | Polyorganosiloxane composition for use in unsaturated elastomer, article made therefrom, and associated method | CONTINENTAL AG (DE) | 2011-12-27 | — | — | US | disclosed |
| EP-1960455-B1 | POLYORGANOSILOXANE COMPOSITION FOR USE IN UNSATURATED ELASTOMER, ARTICLE MADE THEREFROM, AND ASSOCIATED METHOD | CONTINENTAL REIFEN DEUTSCHLAND (DE) | 2011-06-08 | — | — | EP | disclosed |
| US-7776967-B2 | Polyorganosiloxane composition for use in unsaturated elastomer, article made therefrom, and associated method | CONTINENTAL AG (DE) | 2010-08-17 | — | — | US | disclosed |
| US-7652162-B2 | Polydimethyldiloxane having unsaturated end groups reacted with thioacetic acid; vulcanization of natural and synthetic rubbers compounded with carbon black, stearicacid, zinc oxide and deblocking agents; curing; improved mechanical properties,particularly tensile strength, modulus | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1960455-A1 | POLYORGANOSILOXANE COMPOSITION FOR USE IN UNSATURATED ELASTOMER, ARTICLE MADE THEREFROM, AND ASSOCIATED METHOD | Continental Aktiengesellschaft (DE) | 2008-08-27 | — | — | EP | disclosed |
| EP-1960454-A1 | POLYORGANOSILOXANE COMPOSITION FOR USE IN UNSATURATED ELASTOMER, ARTICLE MADE THEREFROM, AND ASSOCIATED METHOD | Continental AG (DE) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007078695-A1 | POLYORGANOSILOXANE COMPOSITION FOR USE IN UNSATURATED ELASTOMER, ARTICLE MADE THEREFROM, AND ASSOCIATED METHOD | CONTINENTAL AG (DE) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007078735-A1 | POLYORGANOSILOXANE COMPOSITION, AND ASSOCIATED METHOD | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
| WO-2007078696-A1 | POLYORGANOSILOXANE COMPOSITION FOR USE IN UNSATURATED ELASTOMER, ARTICLE MADE THEREFROM, AND ASSOCIATED METHOD | CONTINENTAL AG (DE) | 2007-07-12 | — | — | WO | disclosed |
| US-20070142553-A1 | Polyorganosiloxane composition for use in unsaturated elastomer, article made therefrom, and associated method | GENERAL ELECTRIC COMPANY (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070142598-A1 | Polydimethyldiloxane having unsaturated end groups reacted with thioacetic acid; vulcanization of natural and synthetic rubbers compounded with carbon black, stearicacid, zinc oxide and deblocking agents; curing; improved mechanical properties,particularly tensile strength, modulus | GENERAL ELECTRIC COMPANY (US) | 2007-06-21 | — | — | US | disclosed |
| US-20070142552-A1 | Polyorganosiloxane composition for use in unsaturated elastomer, article made therefrom, and associated method | GENERAL ELECTRIC COMPANY (US) | 2007-06-21 | — | — | US | disclosed |
| WO-2004008550-A2 | RAPID LOW-TEMPERATURE SYNTHESIS OF QUANTUM DOTS | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
| WO-1992001476-A1 | NOVEL DRUG DELIVERY SYSTEMS FOR PROTEINS AND PEPTIDES USING ALBUMIN AS A CARRIER MOLECULE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1992-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243501-A1 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS | HDAC1, HDAC11, HDAC2 | LMNA 1949/4885MAPT 4020/4885TSHR 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.