Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | F7 | P08709 | 2/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889885 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6884903 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL11739620 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6888186 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL1923766 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6891959 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL3652371 | 1.00 | LMNA (0.60) | LMNAMAPTTSHRNFKB1PMP22 | |
| SCHEMBL6890958 | 0.97 | — | — | |
| SCHEMBL6067655 | 0.90 | — | — | |
| SCHEMBL7640627 | 0.80 | FAAH (0.54) | LMNAMAPTABCC4TERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2175863-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | Eastern Virginia Medical School (US) | 2010-04-21 | — | — | EP | claimed |
| WO-2009009625-A2 | SUBSTITUTED NUCLEOSIDE DERIVATIVES WITH ANTIVIRAL AND ANTIMICROBIAL PROPERTIES | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2009-01-15 | — | — | WO | claimed |
| US-20230173077-A1 | FATTY ACYL AND FATTY ETHER CONJUGATES OF REMDESIVIR AND ITS ACTIVE METABOLITES AS ANTIVIRALS | AJK Biopharmaceutical, LLC | 2023-06-08 | — | — | US | disclosed |
| WO-2021222807-A1 | FATTY ACYL AND FATTY ETHER CONJUGATES OF REMDESIVIR AND ITS ACTIVE METABOLITES AS ANTIVIRALS | AJK PHARMACEUTICAL LLC (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2004008550-A2 | RAPID LOW-TEMPERATURE SYNTHESIS OF QUANTUM DOTS | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230173077-A1 | FATTY ACYL AND FATTY ETHER CONJUGATES OF REMDESIVIR AND ITS ACTIVE METABOLITES AS ANTIVIRALS | ELOVL6, FADS2, FASN | LMNA 2735/4885MAPT 3626/4885TSHR 3779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.