SCHEMBL28529442

SCHEMBL28529442

O=C(CC(CCO)c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.59
L3MBTL1 Q9Y468 3/20 0.55
TSHR P16473 1/20 0.52
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
NPSR1 Q6W5P4 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.49
HTT P42858 1/20 0.49
PTPN1 P18031 2/20 0.47
HPGD P15428 2/20 0.46
MAPK1 P28482 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9066674 0.87 ATM (0.74) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL12001995 0.84 ATM (0.62) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL1923826 0.83 GABBR2 (0.63) TSHRKMT2AMEN1KDM4EMAPT
SCHEMBL8087232 0.83 ATM (0.56) ATML3MBTL1TSHRNPSR1KDM4E
SCHEMBL8431654 0.83 L3MBTL1 (0.74) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL16616451 0.81 ATM (0.68) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL28053721 0.81 ATM (0.55) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL2581702 0.80 ATM (0.66) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL28114650 0.80 ATM (0.66) ATML3MBTL1TSHRKMT2AMEN1
SCHEMBL12158645 0.80 ATM (0.66) ATML3MBTL1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321402-B Method for preparing 2-hydroxyethyl phenyl ketone by coupling two components 西安石油大学 2022-11-29 CN disclosed
CN-112321401-A Method for preparing 2-hydroxyethyl phenyl ketone by catalytic oxidation of isochroman 西安石油大学 2021-02-05 CN disclosed
CN-112321402-A Method for preparing 2-hydroxyethyl phenyl ketone by coupling two components 西安石油大学 2021-02-05 CN disclosed