SCHEMBL1923917

SCHEMBL1923917

OB(O)Oc1ccc(Cc2ccc(Br)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
APP P05067 1/20 0.40
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
IDO1 P14902 2/20 0.39
MAOB P27338 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
TSHR P16473 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
SRD5A2 P31213 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
GAA P10253 1/20 0.37
RAB9A P51151 1/20 0.37
PPARD Q03181 1/20 0.36
LTA4H P09960 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2150297 0.87 CA2 (0.48) MAPTAPPRXRARXRBMAOB
SCHEMBL28077460 0.83 LTA4H (0.55) SRD5A2L3MBTL1LTA4HHTT
SCHEMBL29706415 0.80 MAPK1 (0.44) MAPTMAOBCA1CA2TSHR
SCHEMBL8698899 0.78 TRPA1 (0.39) APPRXRARXRBMAOBTSHR
SCHEMBL3334615 0.76 CYP2A6 (0.57) IDO1TSHRTAAR1ESR1ESR2
SCHEMBL30330993 0.76 CYP2A6 (0.57) IDO1TSHRTAAR1ESR1ESR2
SCHEMBL3800806 0.76 CA1 (0.38) CA1CA2TSHRMEN1KMT2A
SCHEMBL1251529 0.76 LTA4H (0.50) CA1CA2TSHRMEN1KMT2A
SCHEMBL28463108 0.75 CA1 (0.38) MAPTMAOBCA1CA2TSHR
SCHEMBL27489645 0.75 TDP1 (0.43) CA1CA2FFAR1FFAR4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1840182-B1 Compound for organic electroluminescence and organic electroluminescent device SEIKO EPSON CORP (JP) 2011-06-08 EP disclosed
US-7727642-B2 Light emitting polymer dopant including the units: 3,4,7,12-tetraphenylbenzo[k]fluoranthene, triphenylamine, 9,9-dialkyl- or diaryl-substituted fluorene and optionally diphenylmethane and alkyl- or arylbenzene; high efficiency of light emission and long life span SEIKO EPSON CORPORATION (JP) 2010-06-01 US disclosed
US-7727641-B2 Compound for organic electroluminescence and organic electroluminescent device SEIKO EPSON CORPORATION (JP) 2010-06-01 US disclosed
US-20070244295-A1 Light emitting polymer dopant including the units: 3,4,7,12-tetraphenylbenzo[k]fluoranthene, triphenylamine, 9,9-dialkyl- or diaryl-substituted fluorene and optionally diphenylmethane and alkyl- or arylbenzene; high efficiency of light emission and long life span SEIKO EPSON CORPORATION (JP) 2007-10-18 US disclosed
EP-1840182-A2 Compound for organic electroluminescence and organic electroluminescent device SEIKO EPSON CORPORATION (JP) 2007-10-03 EP disclosed
US-20070221915-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICE SEIKO EPSON CORPORATION (JP) 2007-09-27 US disclosed