Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25132825 | 0.98 | PDE10A (0.32) | TP53KDM4EATML3MBTL1SIRT2 | |
| SCHEMBL25628637 | 0.97 | KDM4E (0.35) | TP53KDM4EATML3MBTL1SIRT2 | |
| SCHEMBL24914965 | 0.97 | KDM4E (0.36) | TP53KDM4EATML3MBTL1SIRT2 | |
| SCHEMBL19130145 | 0.95 | TP53 (0.32) | TP53KDM4EATML3MBTL1SIRT2 | |
| SCHEMBL19129999 | 0.95 | ALDH1A1 (0.31) | TP53KDM4EATML3MBTL1TSHR | |
| SCHEMBL19129940 | 0.95 | ALDH1A1 (0.31) | TP53KDM4EATML3MBTL1TSHR | |
| SCHEMBL19239292 | 0.95 | TP53 (0.32) | TP53KDM4EATML3MBTL1PDE10A | |
| SCHEMBL24217365 | 0.94 | KDM4E (0.36) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21666978 | 0.94 | PTGER4 (0.34) | TP53KDM4EATML3MBTL1TSHR | |
| SCHEMBL19130143 | 0.93 | KDM4E (0.35) | TP53KDM4EATML3MBTL1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-9876181-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-01-23 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170237017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | DDT, ETFA, TST | TP53 4509/4885KDM4E 1629/4885ATM 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.