SCHEMBL24914965

SCHEMBL24914965

c1ccc(-c2nc(-c3cccc(-n4c5ccccc5c5c6c7ccccc7n(-c7ccccc7)c6ccc54)c3)nc(-c3cccc4oc5ccccc5c34)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.36
ATM Q13315 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
SMN1; SMN2 Q16637 4/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32
PDE10A Q9Y233 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TSHR P16473 3/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
BRCA1 P38398 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19239271 0.97 TP53 (0.33) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL19239292 0.96 TP53 (0.32) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL25628637 0.96 KDM4E (0.35) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL25132825 0.95 PDE10A (0.32) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL25964583 0.94 L3MBTL1 (0.37) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL19130145 0.94 TP53 (0.32) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL21666977 0.94 KDM4E (0.35) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL19130143 0.94 KDM4E (0.35) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL22296476 0.94 MAPT (0.34) KDM4EATML3MBTL1SMN1; SMN2LMNA
SCHEMBL19239288 0.94 KDM4E (0.36) KDM4EATML3MBTL1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-18 US disclosed
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2023-05-18 US disclosed
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157165-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, MCM2, MAL2 KDM4E 3500/4885ATM 2480/4885L3MBTL1 844/4885
US-20230019297-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERT, TELO2, SOD1 KDM4E 3351/4885ATM 2183/4885L3MBTL1 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.