Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.64 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.63 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.53 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18779462 | 0.87 | MAPT (0.63) | BCL2L1POLBPDE7AMAPTAPEX1 | |
| SCHEMBL10650251 | 0.87 | MAPT (0.79) | BCL2L1POLBPDE7APDE7BMAPT | |
| SCHEMBL1924145 | 0.86 | BCL2L1 (0.64) | BCL2L1POLBPLA2G4APDE7APDE7B | |
| SCHEMBL18779457 | 0.86 | ALDH1A1 (0.64) | BCL2L1POLBPDE7AMAPTAPEX1 | |
| SCHEMBL1455693 | 0.86 | PDE7A (0.64) | BCL2L1POLBPDE7APDE7BMAPT | |
| SCHEMBL18779432 | 0.86 | ALDH1A1 (0.74) | BCL2L1POLBPDE7AMAPTAPEX1 | |
| SCHEMBL19048781 | 0.84 | MAPT (0.62) | BCL2L1POLBPLA2G4APDE7APDE7B | |
| SCHEMBL1924148 | 0.84 | BCL2L1 (0.67) | BCL2L1POLBPLA2G4APDE7APDE7B | |
| SCHEMBL4002024 | 0.84 | POLB (0.61) | BCL2L1POLBPLA2G4APDE7APDE7B | |
| SCHEMBL4001613 | 0.83 | BCL2L1 (0.60) | BCL2L1POLBPLA2G4APDE7APDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1993367-B | Fused pyrimidine derivatives and xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO | 2012-05-30 | — | — | CN | disclosed |
| EP-1757610-B1 | CONDENSED PYRIMIDINE DERIVATIVE AND XANTHINE OXIDASE INHIBITOR | NIPPON CHEMIPHAR CO (JP) | 2011-06-08 | — | — | EP | disclosed |
| US-7598254-B2 | Substituted 1,3-thiazolo[5,4-d]pyrimidines as xanthine oxidase inhibitors | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20070293512-A1 | Condensed Pyrimidine Deriviative and Xanthine Oxidase Inhibitor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2007-12-20 | — | — | US | disclosed |
| CN-1993367-A | Condensed pyrimidine derivative and xanthine oxidase inhibitor | NIPPON CHEMIPHAR CO (JP) | 2007-07-04 | — | — | CN | disclosed |
| EP-1757610-A1 | CONDENSED PYRIMIDINE DERIVATIVE AND XANTHINE OXIDASE INHIBITOR | Nippon Chemiphar Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| CN-1310621-A | Substituted anilide compounds and methods | SMITHKLINE BEECHAM CORP (US) | 2001-08-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293512-A1 | Condensed Pyrimidine Deriviative and Xanthine Oxidase Inhibitor | XDH, SQOR, PNPO | BCL2L1 4209/4885POLB 197/4885PLA2G4A 3771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.