Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810670 | 0.80 | ELANE (0.43) | ELANEALDH1A1BACE1NPSR1L3MBTL1 | |
| SCHEMBL18805033 | 0.71 | ELANE (0.42) | ELANEALDH1A1BACE1NPSR1L3MBTL1 | |
| SCHEMBL14113510 | 0.71 | LMNA (0.37) | ALDH1A1NPSR1LMNATSHR | |
| SCHEMBL22015030 | 0.70 | GAA (0.48) | ELANEALDH1A1BACE1L3MBTL1CTSG | |
| SCHEMBL8123163 | 0.67 | MAOA (0.41) | ELANENPSR1L3MBTL1LMNAHTT | |
| SCHEMBL16174713 | 0.67 | ELANE (0.44) | ELANEALDH1A1L3MBTL1HTTCTSG | |
| SCHEMBL13562898 | 0.66 | MAOA (0.43) | ELANEALDH1A1BACE1NPSR1TSHR | |
| SCHEMBL4698495 | 0.66 | MEN1 (0.42) | ELANEBACE1NPSR1L3MBTL1LMNA | |
| SCHEMBL16174913 | 0.66 | ELANE (0.51) | ELANEALDH1A1BACE1L3MBTL1HTT | |
| SCHEMBL3966742 | 0.66 | ELANE (0.42) | ELANENPSR1L3MBTL1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2017-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233405-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MYC, MYCBP, MYCBP2 | ELANE 3968/4885ALDH1A1 3226/4885BACE1 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.