Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | USP2 | O75604 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19240049 | 0.97 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL19239992 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNATDP1MAPK1MEN1 | |
| SCHEMBL19239994 | 0.78 | MEN1 (0.37) | ALDH1A1CYP3A4LMNATSHRTDP1 | |
| SCHEMBL19240023 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL12864660 | 0.73 | TSHR (0.47) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL19240032 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL4544744 | 0.69 | TSHR (0.50) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL12758245 | 0.69 | TSHR (0.50) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL257295 | 0.68 | CYP3A4 (0.70) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL4544789 | 0.68 | RECQL (0.46) | ALDH1A1CYP3A4CA2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |