Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19240081 | 0.87 | PRSS1 (0.36) | ALDH1A1CYP3A4CA2TSHRPRSS1 | |
| SCHEMBL19038950 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL19240049 | 0.80 | ALDH1A1 (0.43) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL22484311 | 0.79 | MAPT (0.44) | ALDH1A1CYP3A4TSHRTDP1ATM | |
| SCHEMBL19240024 | 0.79 | GLO1 (0.41) | ALDH1A1TDP1LMNAMAPK1MEN1 | |
| SCHEMBL19240073 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL19240032 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL4544789 | 0.72 | RECQL (0.46) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL13855938 | 0.72 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CA2TSHRTDP1 | |
| SCHEMBL4544744 | 0.71 | TSHR (0.50) | ALDH1A1CYP3A4CA2TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |