SCHEMBL4544789

SCHEMBL4544789

CCCCC(CC)COC(=O)C(=CC=CN1CCCCC1)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RECQL P46063 2/20 0.46
▸ ALDH1A1 P00352 7/20 0.43
▸ CYP3A4 P08684 4/20 0.43
▸ CA2 P00918 3/20 0.43
▸ TSHR P16473 3/20 0.43
▸ TDP1 Q9NUW8 2/20 0.42
▸ ATM Q13315 1/20 0.42
▸ LMNA P02545 3/20 0.40
▸ GAA P10253 1/20 0.40
▸ MAPK1 P28482 3/20 0.40
▸ PRSS1 P07477 1/20 0.39
▸ PRSS2 P07478 1/20 0.39
▸ PRSS3 P35030 1/20 0.39
▸ HSD17B10 Q99714 1/20 0.35
▸ CA1 P00915 1/20 0.34
▸ MMP9 P14780 1/20 0.33
▸ MMP8 P22894 1/20 0.33
▸ MMP14 P50281 1/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19240032 0.95 ALDH1A1 (0.47) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL13855938 0.91 ALDH1A1 (0.51) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL14768457 0.77 ALDH1A1 (0.48) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL14095054 0.77 ALDH1A1 (0.48) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL12101256 0.77 ALDH1A1 (0.48) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL14095058 0.77 RECQL (0.72) RECQLALDH1A1ATMLMNAGAA
SCHEMBL12758245 0.74 TSHR (0.50) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL4544744 0.74 TSHR (0.50) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL15632856 0.74 CYP3A4 (0.62) RECQLALDH1A1CYP3A4CA2TSHR
SCHEMBL14456204 0.72 ALDH1A1 (0.49) RECQLALDH1A1CYP3A4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178601-B2 Polymer film, polarizing plate protective film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-05-15 — — US disclosed
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 — — US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 — — US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090080074-A1 POLYMER FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE RPA3, RTF1, RPA1 RECQL 328/4885ALDH1A1 3470/4885CYP3A4 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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