Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BUB1 | O43683 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109819 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAOAMAOBMAPTL3MBTL1 | |
| SCHEMBL12260834 | 0.78 | ALDH1A1 (0.66) | APPALDH1A1KMT2AHTTLMNA | |
| SCHEMBL13317581 | 0.73 | METAP1 (0.58) | APPALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL14574020 | 0.73 | ALDH1A1 (0.62) | APPALDH1A1KMT2AHTTLMNA | |
| SCHEMBL19240095 | 0.71 | APP (0.43) | APPALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13317579 | 0.71 | METAP1 (0.60) | APPALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL9889248 | 0.70 | APP (0.44) | APPALDH1A1MAPTKMT2AHTT | |
| SCHEMBL19240076 | 0.69 | ALDH1A1 (0.47) | APPALDH1A1MAOAMAPTL3MBTL1 | |
| SCHEMBL2025945 | 0.68 | ALDH1A1 (0.51) | APPALDH1A1MAPTL3MBTL1KMT2A | |
| SCHEMBL19240074 | 0.68 | ALDH1A1 (0.46) | APPALDH1A1MAOAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | MERCK SHARP & DOHME CORP. (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | BACE1, BACE2, APP | APP 3/4885ALDH1A1 752/4885MAOA 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.