Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 4/20 | 0.60 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13317581 | 0.87 | METAP1 (0.58) | METAP1ALDH1A1RAB9AKMT2AMAPT | |
| SCHEMBL13317593 | 0.81 | METAP1 (0.55) | METAP1ALDH1A1RAB9AKMT2AMAPT | |
| SCHEMBL14839892 | 0.80 | ALDH1A1 (0.53) | METAP1F2SIRT2SIRT1SIRT3 | |
| SCHEMBL13848519 | 0.76 | METAP1 (1.00) | METAP1F2SIRT2SIRT1SIRT3 | |
| SCHEMBL4044276 | 0.76 | METAP1 (1.00) | METAP1F2SIRT2SIRT1SIRT3 | |
| SCHEMBL13848138 | 0.74 | METAP1 (0.51) | METAP1F2SIRT2SIRT1SIRT3 | |
| SCHEMBL12260834 | 0.73 | ALDH1A1 (0.66) | ALDH1A1RAB9AKMT2ALMNAMAPK1 | |
| SCHEMBL19240097 | 0.71 | APP (0.44) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL10947962 | 0.70 | ALDH1A1 (0.53) | SIRT2SIRT1SIRT5ALDH1A1KMT2A | |
| SCHEMBL10947969 | 0.70 | ALDH1A1 (0.53) | SIRT2SIRT1SIRT5ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728222-B2 | A photoelectric conversion device comprising an organic dye-sensitizing semiconductor fine particle thin film is prepared by using a dye having a barbituric acid structure as a partial structure and by adsorbing the dye on a semiconductor thin | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7728222-B2 | A photoelectric conversion device comprising an organic dye-sensitizing semiconductor fine particle thin film is prepared by using a dye having a barbituric acid structure as a partial structure and by adsorbing the dye on a semiconductor thin | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2010-06-01 | — | — | US | disclosed |