SCHEMBL9889248

SCHEMBL9889248

CC1(C)CC(=O)C(=C/C=C/N(Cc2ccccc2)Cc2ccccc2)C(=O)C1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 1/20 0.44
▸ ALDH1A1 P00352 5/20 0.38
▸ LMNA P02545 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ CYP11B2 P19099 1/20 0.38
▸ ALPL P05186 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ MAPT P10636 2/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ APEX1 P27695 1/20 0.36
▸ TP53 P04637 2/20 0.36
▸ HTT P42858 1/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ CXCR2 P25025 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889238 0.80 APP (0.44) APPALDH1A1LMNACYP2C9CYP2C19
SCHEMBL9889252 0.75 MAOB (0.39) APPALDH1A1MAPTPOLBKMT2A
SCHEMBL12758233 0.75 APP (0.43) APPALDH1A1MAPTPOLBTP53
SCHEMBL19240036 0.73 APP (0.43) APPALDH1A1HPGDMAPTPOLB
SCHEMBL9889234 0.72 APP (0.41) APPALDH1A1MAPTNPSR1POLB
SCHEMBL4544722 0.72 APP (0.41) APPALDH1A1HPGDALPLMAPT
SCHEMBL12310447 0.72 APP (0.41) APPALDH1A1HPGDMAPTPOLB
SCHEMBL12260820 0.72 APP (0.41) APPALDH1A1MAPTPOLBTP53
SCHEMBL13855924 0.72 POLB (0.61) APPALDH1A1HPGDMAPTNPSR1
SCHEMBL10098421 0.72 POLB (0.61) APPALDH1A1HPGDMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 — — US disclosed
US-8652364-B2 Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound FUJIFILM CORPORATION (JP) 2014-02-18 — — US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 — — US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 — — US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 — — US disclosed
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND FUJIFILM CORPORATION (JP) 2011-09-15 — — US disclosed
US-20110057155-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-03-10 — — US disclosed
US-20110057155-A1 ULTRAVIOLET ABSORBENT COMPOSITION FUJIFILM CORPORATION (JP) 2011-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110220843-A1 POLYMER FILM, ULTRAVIOLET ABSORBER, MEROCYANINE COMPOUND AND PROCESS FOR PREPARING MEROCYANINE COMPOUND HAMP, CRY1, CRY2 APP 97/4885ALDH1A1 1899/4885LMNA 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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