Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046639 | 0.86 | ADORA3 (0.58) | ADORA3TP53PNPLMNAHTT | |
| SCHEMBL9601706 | 0.83 | LMNA (0.57) | TP53PNPLMNAHTTPDE4D | |
| SCHEMBL24499895 | 0.81 | PI4KA (0.61) | ADORA3TP53SMN1; SMN2CYP2C9NFKB1 | |
| SCHEMBL8175179 | 0.81 | PI4KA (0.61) | ADORA3TP53SMN1; SMN2CYP2C9NFKB1 | |
| SCHEMBL20794210 | 0.81 | PI4KA (0.61) | ADORA3TP53SMN1; SMN2CYP2C9NFKB1 | |
| SCHEMBL12832016 | 0.81 | PI4KA (0.61) | ADORA3TP53SMN1; SMN2CYP2C9NFKB1 | |
| SCHEMBL7151977 | 0.81 | PI4KA (0.61) | ADORA3TP53SMN1; SMN2CYP2C9NFKB1 | |
| SCHEMBL10121595 | 0.78 | PI4KA (0.61) | ADORA3TP53SMN1; SMN2CYP2C9NFKB1 | |
| SCHEMBL27364805 | 0.77 | YTHDC1 (0.37) | TP53LMNACYP2C9NFKB1MAPK1 | |
| SCHEMBL19820462 | 0.77 | ADORA2A (0.54) | ADORA3SMN1; SMN2NFKB1PI4KABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2752422-B1 | Stereoselective synthesis of phosphorus containing actives | GILEAD PHARMASSET LLC (US) | 2017-08-16 | — | — | EP | disclosed |