Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.65 |
| ▸ | PNP | P00491 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | PDE2A | O00408 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30694424 | 1.00 | LMNA (0.65) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL8124562 | 1.00 | LMNA (0.65) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL172618 | 1.00 | LMNA (0.65) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL13770324 | 0.89 | PDE4D (0.57) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL23585882 | 0.88 | LMNA (0.57) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL25712959 | 0.88 | LMNA (0.59) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL3239663 | 0.88 | LMNA (0.59) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL9601136 | 0.87 | LMNA (0.55) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL7435133 | 0.87 | LMNA (0.58) | LMNAPDE4DPDE3APNPTP53 | |
| SCHEMBL9601706 | 0.86 | LMNA (0.57) | LMNAPDE4DPDE3APNPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178128-A1 | METHODS OF TREATING MEDICAL CONDITIONS USING ISLATRAVIR OR A RELATED COMPOUND | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-3505527-A1 | CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | Invivogen (FR) | 2019-07-03 | — | — | EP | disclosed |
| EP-2752422-B1 | Stereoselective synthesis of phosphorus containing actives | GILEAD PHARMASSET LLC (US) | 2017-08-16 | — | — | EP | disclosed |
| CN-101668768-A | Preparation A2A-adenosine receptor agonists and polymorphs thereof | CV THERAPEUTICS INC | 2010-03-10 | — | — | CN | disclosed |