Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23585882 | 0.89 | LMNA (0.57) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL10438025 | 0.88 | ALDH1A1 (0.57) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL8124562 | 0.87 | LMNA (0.65) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL172618 | 0.87 | LMNA (0.65) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL30694424 | 0.87 | LMNA (0.65) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL19242566 | 0.87 | LMNA (0.65) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL10379476 | 0.86 | ALDH1A1 (0.56) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL4306006 | 0.85 | LMNA (0.55) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL12154625 | 0.85 | ALDH1A1 (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL9828081 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355135-B1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4997926-A | Viricides | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0355135-A4 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES. | SCRIPPS CLINIC RES (US) | 1990-04-09 | — | — | EP | disclosed |
| EP-0355135-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-02-28 | — | — | EP | disclosed |
| WO-1989004662-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-06-01 | — | — | WO | disclosed |