SCHEMBL3239663

SCHEMBL3239663

Nc1nc(N)c2ncn([C@H]3CC[C@@H](CO)O3)c2n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
ALDH1A1 P00352 1/20 0.59
ALB P02768 1/20 0.59
MAPK1 P28482 1/20 0.59
CYP1A2 P05177 1/20 0.55
AHCY P23526 1/20 0.54
PNP P00491 1/20 0.50
TP53 P04637 1/20 0.50
HTT P42858 1/20 0.50
PDE4D Q08499 1/20 0.50
PDE3A Q14432 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
ADA P00813 1/20 0.46
HSP90B1 P14625 1/20 0.44
ADORA2A P29274 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
NT5E P21589 1/20 0.44
HIF1A Q16665 1/20 0.44
ADORA2B P29275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25712959 1.00 LMNA (0.59) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL21277438 0.90 AHCY (0.49) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL12154625 0.89 ALDH1A1 (0.58) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL7435133 0.89 LMNA (0.58) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL8124562 0.88 LMNA (0.65) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL2808298 0.88 LMNA (0.58) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL887901 0.88 LMNA (0.60) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL22862138 0.88 LMNA (0.58) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL5548925 0.88 LMNA (0.57) LMNAALDH1A1ALBMAPK1CYP1A2
SCHEMBL12149469 0.88 ALDH1A1 (0.57) LMNAALDH1A1ALBMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 225 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12480106-B2 Reactions with non-retroviral reverse transcriptase THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-11-25 US claimed
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLE TX LTD (GB) 2025-10-23 US claimed
CN-117081436-B Permanent magnet synchronous motor current control method and system 中国科学院长春光学精密机械与物理研究所 2025-02-11 CN claimed
WO-2025005781-A1 ANTIMICROBIAL PEPTOID COMPRISING N-TERMINAL METAL COMPLEX 광주과학기술원 2025-01-02 WO claimed
US-20240352073-A1 BICYCLIC PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR JANSSEN BIOTECH INC (US) 2024-10-24 US claimed
US-12083223-B2 Nanolipoprotein particles and related compositions methods and systems for loading RNA LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2024-09-10 US claimed
US-20240209027-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION PEPTIAID INC (JP) 2024-06-27 US claimed
US-20240207186-A1 NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR LOADING RNA LAWRENCE LIVERMORE NATIONAL SECURITY, LLC 2024-06-27 US claimed
CN-114648659-B Light-weight concrete bridge disease identification method based on transfer learning 北京工业大学 2024-06-07 CN claimed
CN-117858889-A Peptides and compositions comprising peptides 肽爱德股份有限公司 2024-04-09 CN claimed
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-06-01 US claimed
US-20200239500-A1 Compositions and Methods for Synthesis of Phosphorylated Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-07-30 US claimed
US-7807653-B2 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2010-10-05 US claimed
US-20070265224-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2007-11-15 US claimed
EP-1485395-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS Biota, Inc. (US) 2004-12-15 EP claimed
WO-2003072757-A9 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA INC (US) 2004-10-21 WO claimed
US-20040059104-A1 Nucleotide mimics and their prodrugs BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2004-03-25 US claimed
WO-2003072757-A2 NUCLEOTIDE MIMICS AND THEIR PRODRUGS BIOTA, INC. (US) 2003-09-04 WO claimed
EP-0374096-B1 COMBINATION THERAPY INVOLVING 2',3'-DIDEOXYPURINE NUCLEOSIDE AND AN INHIBITOR OF PURINE NUCLEOSIDE PHOSPHORYLASE, AND ITS COMPOSITIONS CIBA-GEIGY AG (CH) 1992-12-02 EP claimed
EP-0374096-A1 Combination therapy involving 2',3'-dideoxypurine nucleoside and an inhibitor of purine nucleoside phosphorylase, and its compositions CIBA-GEIGY AG (CH) 1990-06-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070265224-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP LMNA 3677/4885ALDH1A1 2112/4885ALB 4137/4885
US-20250325672-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS ACE2, SARS1, TMPRSS2 LMNA 2785/4885ALDH1A1 4812/4885ALB 816/4885
US-20200239500-A1 Compositions and Methods for Synthesis of Phosphorylated Molecules PIK3CA, CHAMP1, TYMP LMNA 1794/4885ALDH1A1 4371/4885ALB 2637/4885
US-12083223-B2 Nanolipoprotein particles and related compositions methods and systems for loading RNA SARNP, SYNCRIP, AUP1 LMNA 432/4885ALDH1A1 4836/4885ALB 1691/4885
US-20240209027-A1 PEPTIDE AND PEPTIDE-CONTAINING COMPOSITION NGLY1, VIP, HM13 LMNA 2115/4885ALDH1A1 4859/4885ALB 3856/4885
US-11021497-B2 Compositions and methods for synthesis of phosphorylated molecules PIK3CA, CHAMP1, TYMP LMNA 1794/4885ALDH1A1 4371/4885ALB 2637/4885
US-20240352073-A1 BICYCLIC PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL1RN, IL17A LMNA 4245/4885ALDH1A1 4643/4885ALB 2133/4885
US-20240207186-A1 NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR LOADING RNA SARNP, SYNCRIP, AUP1 LMNA 432/4885ALDH1A1 4836/4885ALB 1691/4885
US-20040059104-A1 Nucleotide mimics and their prodrugs NUDT14, ENTPD5, MTAP LMNA 3677/4885ALDH1A1 2112/4885ALB 4137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.